[Advancements in artificial intelligence for the precise diagnosis and treatment of hematological malignancies].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
PMID:

Abstract

Hematological malignancy is a highly heterogeneous disease with complex biological characteristics and diverse clinical manifestations. Therefore, precise diagnosis and treatment are crucial and urgently needed. To further improve the accuracy of diagnosis and prognostication and to promote personalized therapy, artificial intelligence (AI) has been increasingly used. This study reviewed literature published in the last 5 years and summarized the application, benefits, and drawbacks of AI in the diagnosis, treatment, and prognosis of hematologic malignancies. Although AI can effectively improve the accuracy of diagnosis and therapy, low-quality data, poor interpretability of the model, and limited clinical transformation have impeded its popularization and application. In the future, the clinical application of AI in hematologic malignancy can be accelerated by establishing standards for clinical data processing, integrating multimodal information for accurate diagnosis and prognostication, and conducting systematic clinical verification of model algorithms.

Authors

  • H X Yang
    Department of Haematology, State Key Laboratory of Medical Genomics, Shanghai Institute of Haematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • J Xiong
    Department of Vascular Surgery, First Medical Center of Chinese People's Liberation Army General Hospital, Beijing100853, China.
  • W L Zhao
    Department of Haematology, State Key Laboratory of Medical Genomics, Shanghai Institute of Haematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.