Air pollution and prostate cancer: Unraveling the connection through network toxicology and machine learning.

Journal: Ecotoxicology and environmental safety
PMID: 40022828

Abstract

BACKGROUND: In recent years, air pollution has been demonstrated to be associated with the occurrence of various diseases. This study aims to explore the potential association between air pollutants and prostate cancer (PCa) and to identify key genes that may play a critical bridging role in this process.

Authors

  • Yuqi Li
    Department of Urology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Public Center of Experimental Technology, Southwest Medical University, Luzhou, Sichuan 646000, China.
  • Tao Zhou
    Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Zhiyu Liu
    Department of Aerospace and Mechanical Engineering , University of Notre Dame , Notre Dame , Indiana 46556 , United States.
  • Xinyao Zhu
    Key Laboratory of Mechanism Theory and Equipment Design of Ministry of Education, Tianjin University, Tianjin, 300350, China; School of Engineering, University of Warwick, Coventry, CV4 7AL, UK. Electronic address: xinyao_zhu@tju.edu.cn.
  • Qilong Wu
    School of Civil Engineering and Architecture, Shandong University of Science and Technology, Qingdao City, China.
  • Chunyang Meng
    Department of Urology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
  • Qingfu Deng
    Department of Urology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

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