Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?

Journal: Journal of neuroengineering and rehabilitation
PMID: 39920813

Abstract

BACKGROUND: Children with cerebral palsy (CP) often experience gait impairments. Robot-assisted gait training (RGT) has been shown to have beneficial effects in this patient population. However, clinical outcomes of RGT vary substantially from patient to patient. This study explored the hypothesis that clinical outcomes are associated with changes in muscle synergies in response to RGT.

Authors

  • Gloria P Vergara-Diaz
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA.
  • Stefano Sapienza
  • Jean-Francois Daneault
  • Eric Fabara
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA.
  • Catherine Adans-Dester
    Department of Physical Medicine & Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA.
  • Giacomo Severini
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, 300 First Avenue, Charlestown, MA 02129, USA.
  • Vincent C K Cheung
    School of Biomedical and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common Diseases, The Gerald Choa Neuroscience Centre, Brain and Mind Institute, and the Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region.
  • Carmen Echevarría Ruiz de Vargas
    Department of Physical Medicine and Rehabilitation, Hospital Universitario Virgen del Rocío, Seville, Spain.
  • Donna Nimec
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA, USA.
  • Paolo Bonato

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