Syn2Real: synthesis of CT image ring artifacts for deep learning-based correction.

Journal: Physics in medicine and biology
PMID:

Abstract

. We strive to overcome the challenges posed by ring artifacts in x-ray computed tomography (CT) by developing a novel approach for generating training data for deep learning-based methods. Training such networks require large, high quality, datasets that are often generated in the data domain, time-consuming and expensive. Our objective is to develop a technique for synthesizing realistic ring artifacts directly in the image domain, enabling scalable production of training data without relying on specific imaging system physics.. We develop 'Syn2Real,' a computationally efficient pipeline that generates realistic ring artifacts directly in the image domain. To demonstrate the effectiveness of our approach, we train two versions of UNet, vanilla and a high capacity version with self-attention layers that we call UNetpp, withâ„“2and perceptual losses, as well as a diffusion model, on energy-integrating CT images with and without these synthetic ring artifacts.Despite being trained on conventional single-energy CT images, our models effectively correct ring artifacts across various monoenergetic images, at different energy levels and slice thicknesses, from a prototype photon-counting CT system. This generalizability validates the realism and versatility of our ring artifact generation process.Ring artifacts in x-ray CT pose a unique challenge to image quality and clinical utility. By focusing on data generation, our work provides a foundation for developing more robust and adaptable ring artifact correction methods for pre-clinical, clinical and other CT applications.

Authors

  • Dennis Hein
    Department of Physics, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Staffan Holmin
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
  • Vladimir Prochazka
    GE HealthCare, Stockholm, Sweden.
  • Zhye Yin
  • Mats Danielsson
    Department of Physics, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Mats Persson
    Department of Physics, KTH Royal Institute of Technology, Stockholm, Sweden.
  • Ge Wang
    Biomedical Imaging Center, Rensselaer Polytechnic Institute, Troy, New York, USA.