Accuracy of a deep neural network for automated pulmonary embolism detection on dedicated CT pulmonary angiograms.

Journal: European journal of radiology
PMID:

Abstract

PURPOSE: To assess the performance of a Deep Neural Network (DNN)-based prototype algorithm for automated PE detection on CTPA scans.

Authors

  • Emese Zsarnóczay
    Medical Imaging Centre, Semmelweis University, Budapest, Hungary.
  • Saikiran Rapaka
    From the Division of Cardiovascular Imaging, Department of Radiology and Radiological Science (C.T., C.N.D.C., S.B., M.R., T.W.M., T.M.D., R.R.B., U.J.S.), and Division of Cardiology, Department of Medicine (R.R.B., D.H.S., U.J.S.), Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260; Department of Computed Tomography-Research & Development, Siemens Healthcare GmbH, Forchheim, Germany (K.L.G., C.C., C.S., M.S.); Department of Corporate Technology, Siemens SRL, Brasov, Romania (L.M.I.); and Department of Medical Imaging Technologies, Siemens Healthcare, Princeton, NJ (S.R., P.S.).
  • U Joseph Schoepf
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260 (S.S.M., D.M., M.v.A., C.N.D.C., R.R.B., C.T., A.V.S., A.M.F., B.E.J., L.P.G., U.J.S.); Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany (S.S.M., T.J.V.); Stanford University School of Medicine, Department of Radiology, Stanford, Calif (D.M.); Division of Cardiothoracic Imaging, Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (C.N.D.C.); Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC (R.R.B.); Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany (C.T.); Department of Cardiology, Munich University Clinic, Ludwig-Maximilians-University, Munich, Germany (C.T.); Siemens Medical Solutions USA, Malvern, Pa (P.S.); and Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC (A.J.M.).
  • Chiara Gnasso
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20132 Milan, Italy. Electronic address: GNASSO.CHIARA@hsr.it.
  • Milán Vecsey-Nagy
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.
  • Thomas M Todoran
    Division of Cardiology, Department of Medicine, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: todoran@musc.edu.
  • Muhammad Taha Hagar
    Department of Diagnostic and Interventional Radiology, Medical Center, University of Freiburg, Faculty of Medicine, Freiburg, Germany; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA. Electronic address: hagarmu@musc.edus.
  • Dmitrij Kravchenko
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA; Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany.
  • Giuseppe Tremamunno
    Radiology Unit, Department of Medical-Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.
  • Joseph Parkwood Griffith
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: jpg201@musc.edu.
  • Nicola Fink
    Department of Radiology, University Hospital, LMU Munich, Munich, Germany. nicola.fink@med.uni-muenchen.de.
  • Sydney Derrick
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: derricsy@musc.edu.
  • Meredith Bowman
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: bowmamer@musc.edu.
  • Henry Sam
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: samh@musc.edu.
  • Mikayla Tiller
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: tillerm@musc.edu.
  • Kathleen Godoy
    Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA. Electronic address: mkatieg1@gmail.com.
  • Florin Condrea
    Institute of Mathematics of the Romanian Academy "Simion Stoilow, Bucharest, Romania; Advanta, Siemens, 15 Noiembrie Bvd, Brasov, 500097, Romania. Electronic address: florin.condrea@siemens.com.
  • Puneet Sharma
    Digital Technologies and Innovation, Siemens Healthineers, Princeton, NJ, United States.
  • Jim O'Doherty
    Siemens Healthineers, Princeton, New Jersey.
  • Pál Maurovich-Horvat
    Philips Medical Systems Technologies Ltd., Advanced Technologies Center, Haifa, 3100202, Israel.
  • Tilman Emrich
    Department of Diagnostic and Interventional Radiology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany; Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA.
  • Akos Varga-Szemes
    Division of Cardiovascular Imaging, Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29425-2260 (S.S.M., D.M., M.v.A., C.N.D.C., R.R.B., C.T., A.V.S., A.M.F., B.E.J., L.P.G., U.J.S.); Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Frankfurt, Germany (S.S.M., T.J.V.); Stanford University School of Medicine, Department of Radiology, Stanford, Calif (D.M.); Division of Cardiothoracic Imaging, Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (C.N.D.C.); Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, SC (R.R.B.); Department of Cardiology and Intensive Care Medicine, Heart Center Munich-Bogenhausen, Munich, Germany (C.T.); Department of Cardiology, Munich University Clinic, Ludwig-Maximilians-University, Munich, Germany (C.T.); Siemens Medical Solutions USA, Malvern, Pa (P.S.); and Department of Emergency Medicine, Medical University of South Carolina, Charleston, SC (A.J.M.).