Early differential diagnosis models of Talaromycosis and Tuberculosis in HIV-negative hosts using clinical data and machine learning.

Journal: Journal of infection and public health
PMID:

Abstract

BACKGROUND: Talaromyces marneffei is an emerging pathogen, and the number of infections in HIV-negative individuals is increasing. In HIV-negative individuals, talaromycosis is usually misdiagnosed as another disease, especially tuberculosis (TB).

Authors

  • Ye Qiu
    Department of Pharmacy, Changchun University of Chinese Medicine, Changchun, Jilin 130119, P.R. China.
  • Zheng-Tu Li
    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
  • Shi-Xiong Yang
    Department of Tuberculosis Ward, Guangxi Nanning Fourth People's Hospital, Nanning, Guangxi 530021, China.
  • Wu-Shu Chen
    Nanshan School of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
  • Yong Zhang
    Outpatient Department of Hepatitis, The Sixth Affiliated People's Hospital of Dalian Medical University, Dalian, Liaoning, China.
  • Qun-Yu Kong
    Chongqing Nanpeng Artificial Intelligence Technology Research Institute Co., Ltd, Chongqing 401123, China.
  • Ling-Rui Chen
    Chongqing Nanpeng Artificial Intelligence Technology Research Institute Co., Ltd, Chongqing 401123, China.
  • Jie Huang
    Department of Critical Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
  • Lu Lin
    Translational Medicine Research Center, People's Hospital of Henan University of Chinese Medicine, Zhengzhou People's Hospital, Zhengzhou, Henan, 450003, China.
  • Kan Xie
  • Wen Zeng
    Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
  • Shao-Qiang Li
    State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Yang-Qing Zhan
    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.
  • Yan Wang
    College of Animal Science and Technology, Beijing University of Agriculture, Beijing, China.
  • Jian-Quan Zhang
    Department of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong 518000, China. Electronic address: jqzhang2002@126.com.
  • Feng Ye
    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, Guangzhou, China.