Bone-wise rigid registration of femur, tibia, and fibula for the tracking of temporal changes.

Journal: Journal of applied clinical medical physics
PMID: 40066783

Abstract

BACKGROUND: Multiple myeloma (MM) induces temporal alterations in bone structure, such as osteolytic bone lesions, which are challenging to identify through manual image interpretation. The large variation in radiologists' assessments, even at expert centers, further complicates diagnosis. Automatic image analysis methods, including segmentation and registration, can expedite detecting and tracking these bone changes.

Authors

  • Arttu Ruohola
    HUS Diagnostic Center, Department of Radiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Ville Haapamäki
    HUS Diagnostic Center, Department of Radiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Eero Salli
    HUS Medical Imaging Center, Radiology, Helsinki University Hospital and University of Helsinki, P.O. Box 340, FI-00290, Helsinki, Finland. eero.salli@hus.fi.
  • Tuomas Kaseva
    HUS Medical Imaging Center, Radiology, Helsinki University Hospital and University of Helsinki, P.O. Box 340, FI-00290, Helsinki, Finland.
  • Marko Kangasniemi
    HUS Medical Imaging Center, Radiology, University of Helsinki and Helsinki University Hospital, P.O. Box 340 (Haartmaninkatu 4), FI-00290, Helsinki, Finland.
  • Sauli Savolainen
    HUS Medical Imaging Center, Radiology, University of Helsinki and Helsinki University Hospital, P.O. Box 340 (Haartmaninkatu 4), FI-00290, Helsinki, Finland.

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