Hand X-rays findings and a disease screening for Turner syndrome through deep learning model.

Journal: BMC pediatrics
PMID:

Abstract

BACKGROUND: Turner syndrome (TS) is one of the important causes of short stature in girls, but there are cases of misdiagnosis and missed diagnosis in clinical practice. Our aim is to analyze the hand skeletal characteristics of TS patients and establish a disease screening model using deep learning.

Authors

  • Yirou Wang
    Department of Endocrinology, Genetics and Metabolism, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Yumo Wang
    CAS Key Laboratory of Mechanical Behavior and Design of Materials, Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui 230027, People's Republic of China.
  • Feihan Hu
    Department of Endocrinology, Genetics and Metabolism, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Liqi Zhou
    Department of Data Science, School of Statistics and Information, Shanghai University of International Business and Economics, Shanghai, China.
  • Yu Ding
    College of Economics and Management, Nanjing University of Aeronautics and Astronautics, Nanjing, 211106, China.
  • Chen Guo
    Diagnostic Imaging Center, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Yao Chen
    Department of Galactophore Surgery, West China Hospital, Sichuan University, Chengdu, 610041, PR China.
  • Yabin Hu
    Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
  • Shijian Liu
    Shanghai Children's Medical Center, Shanghai, China.
  • Xiumin Wang
    Department of Endocrinology and Metabolism, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China. changguoying@126.com.