The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
40340550
BACKGROUND: Early prediction of pregnancy complications is important for adequate and timely prevention, management, and reducing maternal/fetal pathogenesis.
BACKGROUND: Oral mucosal lesions are widespread globally, have a high prevalence in clinical practice, and significantly impact patients' quality of life. However, their pathogenesis remains unclear. Recent evidences suggested that hematological para...
OBJECTIVE: Neuroserpin, a serine protease inhibitor, is recognized for its anti-inflammatory and neuroprotective properties. Given the central role of inflammation and neurological involvement in the pathophysiology of preeclampsia, this study aimed ...
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
BACKGROUND: Short stature is a prevalent pediatric endocrine disorder for which early detection and prediction are pivotal for improving treatment outcomes. However, existing diagnostic criteria often lack the necessary sensitivity and specificity be...
Cancer control : journal of the Moffitt Cancer Center
40334702
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...
BACKGROUND: The aim of our study was to determine whether the application of machine learning could predict PASC by using diagnoses from primary care and prescribed medication 1 year prior to PASC diagnosis.
BACKGROUND: Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and is closely linked to the gut microbiota. Identifying reproducible and generalizable microbial signatures holds significant potential for enhancing early detection ...
BACKGROUND AND OBJECTIVE: Accurate detection of schizophrenia poses a grand challenge as a complex and heterogeneous mental disorder. Current diagnostic criteria rely primarily on clinical symptoms, which may not fully capture individual differences ...
International journal of rheumatic diseases
40296690
INTRODUCTION: Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the axial skeleton, characterized by immune microenvironment dysregulation and elevated cytokines like TNF-α and IL-17. Mitochondrial oxidative phosphorylation (OXP...