Investigation and validation of genes associated with endoplasmic reticulum stress in diabetic retinopathy using various machine learning algorithms.

Journal: Experimental eye research
PMID: 40043935

Abstract

BACKGROUND: Diabetic retinopathy (DR) is a common complication of diabetes, with Endoplasmic reticulum stress (ERS) playing a key role in cellular adaptation, injury, or apoptosis, impacting disease pathology. This study aimed to identify early diagnostic markers for personalized DR treatment.

Authors

  • Limin Zheng
    Department of Ophthalmology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, No. 368, Jiangdong North Road, Gulou District, Nanjing 210000, Jiangsu Province, China; Department of Ophthalmology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, China.
  • Yaodan Cao
    Department of Ophthalmology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, China.
  • Jinqi Hao
    School of Public Health, Teaching and Research Section of Health Statistics, Baotou Medical College, Baotou City, Inner Mongolia Autonomous Region, China.
  • Yanqin Yu
    School of Public Health, Teaching and Research Section of Epidemiology, Baotou Medical College, Baotou City, Inner Mongolia Autonomous Region, China.
  • Wuyun Lu
    Department of Ophthalmology, The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, China.
  • Tianqi Guo
    Department of Ophthalmology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, No. 368, Jiangdong North Road, Gulou District, Nanjing 210000, Jiangsu Province, China.
  • Songtao Yuan
    Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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