Deep learning models for early and accurate diagnosis of ventilator-associated pneumonia in mechanically ventilated neonates.

Journal: Computers in biology and medicine
PMID:

Abstract

BACKGROUND: Early and accurate confirmation of critically ill neonates with a suspected diagnosis of ventilator-associated pneumonia (VAP) can optimize the therapeutic strategy and avoid unnecessary use of empirical antibiotics. We aimed to examine whether deep learning (DL) methods can assist the diagnosis of VAP of intubated neonates in the neonatal intensive care unit (NICU).

Authors

  • Jen-Fu Hsu
    Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Ying-Chih Lin
    Department of Applied Mathematics, Feng Chia University, Taichung, Taiwan.
  • Chun-Yuan Lin
    Department of Computer Science and Information Engineering, Asia University, Taichung, Taiwan; Department of Computer Science and Information Engineering, Chang Gung University, Taoyuan, Taiwan. Electronic address: cyulin@asia.edu.tw.
  • Shih-Ming Chu
    Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Hui-Jun Cheng
    Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China; Department of Computer Science and Information Engineering, Providence University, Taichung, Taiwan.
  • Fan-Wei Xu
    Department of Applied Mathematics, Feng Chia University, Taichung, Taiwan.
  • Hsuan-Rong Huang
    Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Chen-Chu Liao
    Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Rei-Huei Fu
    Division of Pediatric Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
  • Ming-Horng Tsai
    Division of Neonatology and Pediatric Hematology/Oncology, Department of Pediatrics, Chang Gung Memorial Hospital, Yunlin, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: mingmin.tw@yahoo.com.tw.