Artificial intelligence-enhanced electrocardiography for the identification of a sex-related cardiovascular risk continuum: a retrospective cohort study.

Journal: The Lancet. Digital health
PMID:

Abstract

BACKGROUND: Females are typically underserved in cardiovascular medicine. The use of sex as a dichotomous variable for risk stratification fails to capture the heterogeneity of risk within each sex. We aimed to develop an artificial intelligence-enhanced electrocardiography (AI-ECG) model to investigate sex-specific cardiovascular risk.

Authors

  • Arunashis Sau
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.
  • Ewa Sieliwonczyk
    National Heart and Lung Institute (A.S., K.A.M., L.P., N.B., M.G., E. Sieliwonczyk, K.P., M.A., J.Y.C., H.W., X.S., K.H., S.Z., D.B.K., N.S.P., M.M., J.S.W., F.S.N.), Imperial College London, United Kingdom.
  • Konstantinos Patlatzoglou
    National Heart and Lung Institute (A.S., K.A.M., L.P., N.B., M.G., E. Sieliwonczyk, K.P., M.A., J.Y.C., H.W., X.S., K.H., S.Z., D.B.K., N.S.P., M.M., J.S.W., F.S.N.), Imperial College London, United Kingdom.
  • Libor Pastika
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.
  • Kathryn A McGurk
    National Heart and Lung Institute (A.S., K.A.M., L.P., N.B., M.G., E. Sieliwonczyk, K.P., M.A., J.Y.C., H.W., X.S., K.H., S.Z., D.B.K., N.S.P., M.M., J.S.W., F.S.N.), Imperial College London, United Kingdom.
  • Antônio H Ribeiro
    Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. antonio-ribeiro@ufmg.br.
  • Antonio Luiz P Ribeiro
    Hospital das Clínicas and Faculdade de Medicina, Universidade Federal de Minas Gerais, Av. Prof. Alfredo Balena, 190 - sala 533/Universidade Federal de Minas Gerais (UFMG), Belo Horizonte - MG, Brazil. Electronic address: tom@hc.ufmg.br.
  • Jennifer E Ho
    Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts.
  • Nicholas S Peters
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.
  • James S Ware
    National Heart & Lung Institute & MRC London Institute of Medical Sciences, Imperial College London, London W12 0HS, UK.
  • Upasana Tayal
    National Heart and Lung Institute, Imperial College London, London, UK; Department of Cardiology, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Daniel B Kramer
    Richard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.
  • Jonathan W Waks
    Harvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA, USA.
  • Fu Siong Ng
    National Heart and Lung Institute, Hammersmith Campus, Imperial College London, 72 Du Cane Road, W12 0HS, London, UK.