Deep learning-based normative database of anterior chamber dimensions for angle closure assessment: the Singapore Chinese Eye Study.

Journal: The British journal of ophthalmology
PMID:

Abstract

BACKGROUND/ AIMS: The lack of context for anterior segment optical coherence tomography (ASOCT) measurements impedes its clinical utility. We established the normative distribution of anterior chamber depth (ACD), area (ACA) and width (ACW) and lens vault (LV), and applied percentile cut-offs to detect primary angle closure disease (PACD; ≥180° posterior trabecular meshwork occluded).

Authors

  • Zhi-Da Soh
    Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore.
  • Mingrui Tan
    Institute of High Performance Computing, Agency for Science, Technology and Research (A*Star), 1 Fusionopolis Way, 138632, Singapore. Electronic address: tan_mingrui@ihpc.a-star.edu.sg.
  • Zann Lee
    Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Marco Yu
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Sahil Thakur
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Raghavan Lavanya
    Ocular Epidemiology Research Group, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Monisha Esther Nongpiur
    Singapore Eye Research Institute, Singapore National Eye Centre, 20 College Road, 169856, Singapore; Ophthalmology & Visual Sciences Academic Clinical Programme, Academic Medicine, Duke-NUS Medical School, 8 College Road, 169857, Singapore. Electronic address: monisha.esther.nongpiur@seri.com.sg.
  • Xinxing Xu
    A*STAR, Singapore, Singapore.
  • Victor Koh
    Department of Ophthalmology, National University Hospital, Singapore mgirard@ophthalmic.engineering victor_koh@nuhs.edu.sg.
  • Tin Aung
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Yong Liu
    Department of Critical care medicine, Shenzhen Hospital, Southern Medical University, Guangdong, Shenzhen, China.
  • Ching-Yu Cheng
    Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.