Structure preservation constraints for unsupervised domain adaptation intracranial vessel segmentation.

Journal: Medical & biological engineering & computing
Published Date:

Abstract

Unsupervised domain adaptation (UDA) has received interest as a means to alleviate the burden of data annotation. Nevertheless, existing UDA segmentation methods exhibit performance degradation in fine intracranial vessel segmentation tasks due to the problem of structure mismatch in the image synthesis procedure. To improve the image synthesis quality and the segmentation performance, a novel UDA segmentation method with structure preservation approaches, named StruP-Net, is proposed. The StruP-Net employs adversarial learning for image synthesis and utilizes two domain-specific segmentation networks to enhance the semantic consistency between real images and synthesized images. Additionally, two distinct structure preservation approaches, feature-level structure preservation (F-SP) and image-level structure preservation (I-SP), are proposed to alleviate the problem of structure mismatch in the image synthesis procedure. The F-SP, composed of two domain-specific graph convolutional networks (GCN), focuses on providing feature-level constraints to enhance the structural similarity between real images and synthesized images. Meanwhile, the I-SP imposes constraints on structure similarity based on perceptual loss. The cross-modality experimental results from magnetic resonance angiography (MRA) images to computed tomography angiography (CTA) images indicate that StruP-Net achieves better segmentation performance compared with other state-of-the-art methods. Furthermore, high inference efficiency demonstrates the clinical application potential of StruP-Net. The code is available at https://github.com/Mayoiuta/StruP-Net .

Authors

  • Sizhe Zhao
    Key Laboratory of Intelligent Computing in Medical Image, Ministry of Education, Northeastern University, Shenyang, Liaoning, China.
  • Qi Sun
    Department of Orthopedics, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai, 200072, P.R.China.
  • Jinzhu Yang
    College of Information Science and Engineering, Northeastern University, 110819, Shenyang, China.
  • Yuliang Yuan
    Chongqing Cancer Multiomics Big Data Application Engineering Research Center, Chongqing University Cancer Hospital, Chongqing 400030, China.
  • Yan Huang
    Department of Neurology, University of Texas Health Science Center at Houston, Houston, TX.
  • Zhiqing Li
    Department of Urology, Yan'an Hospital of Traditional Chinese Medicine, Yan'an 716000, Shaanxi, China.