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Unsupervised Machine Learning

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Unsupervised machine learning-based stratification and immune deconvolution of liver hepatocellular carcinoma.

BMC cancer
BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer and a leading cause of cancer-related deaths globally. The tumour microenvironment (TME) influences treatment response and prognosis, yet its heterogeneity remains ...

Threshold-based exploitation of noisy label in black-box unsupervised domain adaptation.

PloS one
How can we perform unsupervised domain adaptation when transferring a black-box source model to a target domain? Black-box Unsupervised Domain Adaptation focuses on transferring the labels derived from a pre-trained black-box source model to an unlab...

TriLex: A fusion approach for unsupervised sentiment analysis of short texts.

PloS one
In recent years, online customer reviews and social media platforms have significantly impacted individuals' daily lives. Despite the generally short nature of textual content on these platforms, they convey a wide range of user sentiments. However, ...

Supervised and unsupervised learning reveal heroin-induced impairments in astrocyte structural plasticity.

Science advances
Astrocytes regulate synaptic activity across large brain territories via their complex, interconnected morphology. Emerging evidence supports the involvement of astrocytes in shaping relapse to opioid use through morphological rearrangements in the n...

Unlocking the soundscape of coral reefs with artificial intelligence: pretrained networks and unsupervised learning win out.

PLoS computational biology
Passive acoustic monitoring can offer insights into the state of coral reef ecosystems at low-costs and over extended temporal periods. Comparison of whole soundscape properties can rapidly deliver broad insights from acoustic data, in contrast to de...

Deconvolution of cell types and states in spatial multiomics utilizing TACIT.

Nature communications
Identifying cell types and states remains a time-consuming, error-prone challenge for spatial biology. While deep learning increasingly plays a role, it is difficult to generalize due to variability at the level of cells, neighborhoods, and niches in...

Unsupervised brain MRI tumour segmentation via two-stage image synthesis.

Medical image analysis
Deep learning shows promise in automated brain tumour segmentation, but it depends on costly expert annotations. Recent advances in unsupervised learning offer an alternative by using synthetic data for training. However, the discrepancy between real...

Optimizing unsupervised feature engineering and classification pipelines for differentiated thyroid cancer recurrence prediction.

BMC medical informatics and decision making
BACKGROUND: Differentiated thyroid cancer (DTC) is a common endocrine malignancy with rising incidence and frequent recurrence, despite a generally favorable prognosis. Accurate recurrence prediction is critical for guiding post-treatment strategies....