Utilizing Pix2Pix conditional generative adversarial networks to recover missing data in preclinical PET scanner sinogram gaps.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PMID:

Abstract

BACKGROUND: The presence of a gap between adjacent detector blocks in Positron Emission Tomography (PET) scanners introduces a partial loss of projection data, which can degrade the image quality and quantitative accuracy of reconstructed PET images. This study suggests a novel approach for filling missing data from sinograms generated from preclinical PET scanners using a combination of an inpainting method and the Pix2Pix conditional generative adversarial network (cGAN).

Authors

  • Zahra Karimi
    Faculty of Physics, University of Isfahan, Isfahan, Iran.
  • Khadijeh Rezaee Ebrahim Saraee
    Faculty of Physics, University of Isfahan, Isfahan, Iran. Electronic address: kh.rezaee@ast.ui.ac.ir.
  • Mohammad Reza Ay
    Research Center for Molecular and Cellular Imaging (RCMCI), Advanced Medical Technologies and Equipment Institute (AMTEI), Tehran University of Medical Sciences (TUMS), Tehran, Iran.
  • Peyman Sheikhzadeh
    Nuclear Medicine Department, IKHC, Faculty of Medicine, Tehran University of Medical Science, Tehran, Iran.