Retraining and evaluation of machine learning and deep learning models for seizure classification from EEG data.

Journal: Scientific reports
PMID:

Abstract

Electroencephalography (EEG) is one of the most used techniques to perform diagnosis of epilepsy. However, manual annotation of seizures in EEG data is a major time-consuming step in the analysis process of EEGs. Different machine learning models have been developed to perform automated detection of seizures from EEGs. However, a large gap is observed between initial accuracies and those observed in clinical practice. In this work, we reproduced and assessed the accuracy of a large number of models, including deep learning networks, for detection of seizures from EEGs. Benchmarking included three different datasets for training and initial testing, and a manually annotated EEG from a local patient for further testing. Random forest and a convolutional neural network achieved the best results on public data, but a large reduction of accuracy was observed testing with the local data, especially for the neural network. We expect that the retrained models and the data available in this work will contribute to the integration of machine learning techniques as tools to improve the accuracy of diagnosis in clinical settings.

Authors

  • Juan Pablo Carvajal-Dossman
    System and computing engineering department, Universidad de Los Andes, Bogota, Colombia.
  • Laura Guio
    HOMI, Fundación Hospital Pediátrico La Misericordia, Bogota, Colombia.
  • Danilo García-Orjuela
    Biotecnología y Genética SAS, Biotecgen, Bogota, Colombia.
  • Jennifer J Guzmán-Porras
    HOMI, Fundación Hospital Pediátrico La Misericordia, Bogota, Colombia.
  • Kelly Garces
    System and computing engineering department, Universidad de Los Andes, Bogota, Colombia.
  • Andres Naranjo
    HOMI, Fundación Hospital Pediátrico La Misericordia, Bogota, Colombia.
  • Silvia Juliana Maradei-Anaya
    HOMI, Fundación Hospital Pediátrico La Misericordia, Bogota, Colombia.
  • Jorge Duitama
    Systems and Computing Engineering Department, Universidad de los Andes, Bogotá, Colombia.