Association Between Risk Factors and Major Cancers: Explainable Machine Learning Approach.

Journal: JMIR cancer
PMID:

Abstract

BACKGROUND: Cancer is a life-threatening disease and a leading cause of death worldwide, with an estimated 611,000 deaths and over 2 million new cases in the United States in 2024. The rising incidence of major cancers, including among younger individuals, highlights the need for early screening and monitoring of risk factors to manage and decrease cancer risk.

Authors

  • Xiayuan Huang
    Department of Biostatistics, Yale University School of Public Health, New Haven, CT 06510, United States.
  • Shushun Ren
    School of Nursing, University of Michigan-Ann Arbor, 400 North Ingalls Street, Ann Arbor, MI, 48109, United States, 1 7347633705, 1 7346472416.
  • Xinyue Mao
    College of Literature Science and the Arts, University of Michigan-Ann Arbor, Ann Arbor, MI, United States.
  • Sirui Chen
    School of Electronics and Information Engineering, Tongji University, Shanghai 201804, China.
  • Elle Chen
    School of Nursing, University of Michigan-Ann Arbor, 400 North Ingalls Street, Ann Arbor, MI, 48109, United States, 1 7347633705, 1 7346472416.
  • Yuqi He
    Department of Gastroenterology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
  • Yun Jiang