A comparative analysis of large language models versus traditional information extraction methods for real-world evidence of patient symptomatology in acute and post-acute sequelae of SARS-CoV-2.

Journal: PloS one
PMID:

Abstract

BACKGROUND: Patient symptoms, crucial for disease progression and diagnosis, are often captured in unstructured clinical notes. Large language models (LLMs) offer potential advantages in extracting patient symptoms compared to traditional rule-based information extraction (IE) systems.

Authors

  • Vedansh Thakkar
    Department of Surgery, University of Minnesota, Minneapolis, Minnesota, United States of America.
  • Greg M Silverman
  • Abhinab Kc
    University of Minnesota Medical School, Minneapolis, Minnesota, United States of America.
  • Nicholas E Ingraham
    Division of Pulmonary and Critical Care, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America.
  • Emma K Jones
    Department of Surgery, University of Minnesota, Minneapolis, MN.
  • Samantha King
    Department of Surgery, University of Washington, Seattle, Washington, United States of America.
  • Genevieve B Melton
    Institute for Health Informatics, University of Minnesota, Minneapolis, Minnesota, USA.
  • Rui Zhang
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Christopher J Tignanelli
    From the Department of Surgery (C.J.T., G.B., G.B.M.), University of Minnesota, Minneapolis, Minnesota; Institute for Health Informatics (C.J.T., G.M.S., R.F., R.M., B.C.K., S.P., E.A.L., G.B.M.), University of Minnesota, Minneapolis, Minnesota; Department of Surgery (C.J.T., J.L.G.), North Memorial Health Hospital, Robbinsdale, Minnesota; North Memorial Health Hospital Emergency Medical Services (A.L.T.), Robbinsdale, Minnesota; and Department of Emergency Medicine (J.W.L.), North Memorial Health Hospital Emergency Medical Services, Robbinsdale, Minnesota.