Evaluation of deep learning-based scatter correction on a long-axial field-of-view PET scanner.

Journal: European journal of nuclear medicine and molecular imaging
Published Date:

Abstract

OBJECTIVE: Long-axial field-of-view (LAFOV) positron emission tomography (PET) systems allow higher sensitivity, with an increased number of detected lines of response induced by a larger angle of acceptance. However this extended angle increases the number of multiple scatters and the scatter contribution within oblique planes. As scattering affects both quality and quantification of the reconstructed image, it is crucial to correct this effect with more accurate methods than the state-of-the-art single scatter simulation (SSS) that can reach its limits with such an extended field-of-view (FOV). In this work, which is an extension of our previous assessment of deep learning-based scatter estimation (DLSE) carried out on a conventional PET system, we aim to evaluate the DLSE method performance on LAFOV total-body PET.

Authors

  • Baptiste Laurent
    LaTIM, INSERM, UMR 1101, UBO, Brest, France.
  • Alexandre Bousse
    LaTIM, Inserm UMR 1101, Université de Bretagne Occidentale, 29238 Brest, France.
  • Thibaut Merlin
    LaTIM, INSERM, UMR 1101, UBO, Brest, France.
  • Axel Rominger
  • Kuangyu Shi
    Universitätsklinik für Nuklearmedizin, Inselspital University Hospital Bern, University of Bern, Bern, Switzerland.
  • Dimitris Visvikis
    LaTIM, INSERM, UMR 1101, Brest 29609, France.