Large Scale MRI Collection and Segmentation of Cirrhotic Liver.

Journal: Scientific data
Published Date:

Abstract

Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive assessment, accurately segmenting cirrhotic livers presents substantial challenges due to morphological alterations and heterogeneous signal characteristics. Deep learning approaches show promise for automating these tasks, but progress has been limited by the absence of large-scale, annotated datasets. Here, we present CirrMRI600+, the first comprehensive dataset comprising 628 high-resolution abdominal MRI scans (310 T1-weighted and 318 T2-weighted sequences, totaling nearly 40,000 annotated slices) with expert-validated segmentation labels for cirrhotic livers. The dataset includes demographic information, clinical parameters, and histopathological validation where available. Additionally, we provide benchmark results from 11 state-of-the-art deep learning experiments to establish performance standards. CirrMRI600+ enables the development and validation of advanced computational methods for cirrhotic liver analysis, potentially accelerating progress toward automated Cirrhosis visual staging and personalized treatment planning.

Authors

  • Debesh Jha
    Department of Information and Communication Engineering, Chosun University, 309 Pilmun-Daero, Dong-Gu, Gwangju 61452, Republic of Korea.
  • Onkar Kishor Susladkar
    Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL, 60611, USA.
  • Vandan Gorade
    Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, USA.
  • Elif Keles
    Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University.
  • Matthew Antalek
    Machine and Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL, United States.
  • Deniz Seyithanoglu
    Machine and Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL, United States.
  • Timurhan Cebeci
    Istanbul University, School of Medicine (Capa), Istanbul, Turkey.
  • Halil Ertugrul Aktas
    Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL, 60611, USA.
  • Gulbiz Dagoglu Kartal
    Istanbul University, School of Medicine (Capa), Istanbul, Turkey.
  • Sabahattin Kaymakoglu
    Istanbul University, School of Medicine (Capa), Istanbul, Turkey.
  • Sukru Mehmet Erturk
    Istanbul University, School of Medicine (Capa), Istanbul, Turkey.
  • Yuri Velichko
    Machine & Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL, 60611, USA.
  • Daniela P Ladner
    Northwestern University Transplant Outcomes Research Collaborative (NUTORC), Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America.
  • Amir A Borhani
    Northwestern University Feinberg School of Medicine, Chicago, IL amir.borhani@northwestern.edu.
  • Alpay Medetalibeyoglu
  • Gorkem Durak
  • Ulas Bagci
    Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.