BACKGROUND: To compare liver image quality and lesion detection using an AI-augmented T1-weighted sequence on hepatobiliary-phase gadoxetate-enhanced magnetic resonance imaging (MRI).
BACKGROUND: Large language models like ChatGPT have demonstrated potential in medical image interpretation, but their efficacy in liver histopathological analysis remains largely unexplored. This study aims to assess ChatGPT-4-vision's diagnostic acc...
BACKGROUND: Adenine base editors (ABEs) enable the conversion of A•T to G•C base pairs. Since the sequence of the target locus influences base editing efficiency, efforts have been made to develop computational models that can predict base editing ou...
BACKGROUND: Dysregulated programmed cell death pathways mechanistically contribute to hepatic inflammation and fibrogenesis in non-alcoholic steatohepatitis (NASH). Identification of cell death genes may offer insights into diagnostic and therapeutic...
Pharmacokinetic data are not generally available for evaluating the toxicological potential of food chemicals. A simplified physiologically based pharmacokinetic (PBPK) model has been established to evaluate internal exposures to chemicals in rats or...
Food research international (Ottawa, Ont.)
40356129
Per- and polyfluoroalkyl substances (PFAS) contamination in aquatic and terrestrial organisms poses significant environmental and health risks. This study quantified 15 PFAS compounds across various tissues (liver, kidney, gill, muscle, skin, lung, b...
BACKGROUND: Hepatic fibrosis (HF) represents a pivotal stage in the progression and potential reversal of cirrhosis, underscoring the importance of early identification and therapeutic intervention to modulate disease trajectory.
Topics in magnetic resonance imaging : TMRI
40249154
OBJECTIVES: To develop and evaluate a deep learning technique for the differentiation of hepatocellular carcinoma (HCC) using "simplified intravoxel incoherent motion (IVIM) parameters" derived from only 3 b-value images.
The safety and efficacy of irreversible electroporation (IRE) in tumor therapy has been validated over many years by clinical application. An in-depth study, however, is required to assess the degree of ablation during the clinical dissemination of t...