In silico design strategies for tubulin inhibitors for the development of anticancer therapies.
Journal:
Expert opinion on drug discovery
Published Date:
Aug 1, 2025
Abstract
INTRODUCTION: Microtubules, composing of α, β-tubulin dimers, are important for cellular processes like proliferation and transport, thereby they become suitable targets for research in cancer. Existing candidates often exhibit off-target effects, necessitating the quest for safer alternatives.
