Multivariate Classification of Adolescent Major Depressive Disorder Using Whole-brain Functional Connectivity.

Journal: Academic radiology
Published Date: Mar 29, 2025

Abstract

RATIONALE AND OBJECTIVES: Adolescent major depressive disorder (MDD) is a serious mental health condition that has been linked to abnormal functional connectivity (FC) patterns within the brain. However, whether FC could be used as a potential biomarker for diagnosis of adolescent MDD is still unclear. The aim of our study was to investigate the potential diagnostic value of whole-brain FC in adolescent MDD.

Authors

  • Zhong Li
    Honghui Hospital, Xi'an Jiaotong University, Xi'an, China.
  • Yanrui Shen
    Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
  • Meng Zhang
    College of Software, Beihang University, Beijing, China.
  • Xuekun Li
    Department of Magnetic Resonance, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Baolin Wu
    Department of Radiology and Huaxi MR Research Center (HMRRC), Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, China; Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, China. Electronic address: WBLlin0129@163.com.

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