Predictive modelling of air pollution affecting human tuberculosis risk on Mainland China.

Journal: Scientific reports
Published Date:

Abstract

In this study, we investigated the correlation between air pollution indicators and pulmonary tuberculosis (TB) incidence and mortality rates across provincial administrative regions of China from January 2013 to December 2020 to develop predictive models using machine learning. Data on TB rates and six air pollution indicators were collected and analyzed for correlations. Regression models were built using six algorithms, among which the random forest (RF) model showed superior performance. SHapley Additive exPlanations analysis helped interpret the RF model's predictions. Seasonal and lag analyses identified a 10-month optimal lag period. Seasonal autoregressive integrated moving average models were used to predict 2020 TB incidence rates, which were validated by comparing them with actual data. The results indicated significant correlations between air pollution and TB rates, highlighting that air pollution data can predict TB incidence and mortality; therefore, air pollution data can help develop public health strategies. This study emphasized the importance of integrating environmental factors into TB control efforts using artificial intelligence.

Authors

  • Boli Qin
    The First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, 530021, Guangxi, People's Republic of China.
  • Rongqing He
    The First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, 530021, Guangxi, People's Republic of China.
  • Xiaopeng Qin
    The First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, 530021, Guangxi, People's Republic of China.
  • Jiayan Jiang
    Xuzhou Medical University, No.209 Tongshan Road, Xuzhou, 221004, Jiangsu, People's Republic of China.
  • Chenxing Zhou
    Department of Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China.
  • Songze Wu
    The First Affiliated Hospital of Guangxi Medical University, No.6 Shuangyong Road, Nanning, 530021, Guangxi, People's Republic of China.
  • Jichong Zhu
    Department of Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China.
  • Shaofeng Wu
    Department of Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China.
  • Jiarui Chen
    Department of Computer and Information Science, Faculty of Science and Technology, University of Macau, Macau, China.
  • Jiang Xue
    Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
  • Kechang He
    HIV/AIDS Clinical Treatment Center of Guangxi (Nanning), The Fourth People's Hospital of Nanning, No. 1, Lane 2, Changgang Road, Nanning, 530023, Guangxi, People's Republic of China.
  • Chong Liu
    * Department of Mechanical Engineering and Automation, Northeastern University, Shenyang 110819, P. R. China.
  • Jie Ma
    Respiratory Department, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
  • Xinli Zhan
    Department of Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical University, Nanning, P.R. China.