The liver reconditioning in critical care medicine.

Journal: Current opinion in anaesthesiology
Published Date: Jun 24, 2025

Abstract

PURPOSE OF REVIEW: Machine perfusion has emerged as a transformative alternative to static cold storage in liver transplantation, necessitating a comprehensive review of current evidence. This article examines recent advances in preservation techniques, therapeutic applications, and future directions of machine perfusion technologies.

Authors

  • Luigi La Via
    Department of Anaesthesia and Intensive Care, University Hospital Policlinico "G. Rodolico-San Marco", Catania.
  • Christian Zanza
    Department of Systems Medicine, Geriatric Medicine Residency Program - University of Rome "Tor Vergata", Rome.
  • Manfredi Tesauro
    Department of Systems Medicine, Geriatric Medicine Residency Program - University of Rome "Tor Vergata", Rome.
  • Francesca Rubulotta
    Department of Critical Care Medicine, McGill University, Montreal, QC, Canada.
  • Raymond Planinsic
    Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Yaroslava Longhitano
    Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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