Development of an Automated Classification System for Medication-Related Incident Factors: A Practical Approach to Enhancing Patient Safety Management.

Journal: Studies in health technology and informatics
Published Date:

Abstract

Analyzing medication-related incident reports is crucial for patient safety; however, systematically extracting the underlying factors contributing to incident occurrence remains challenging. We developed a multi-label classifier that automatically identified incident factors from 1,212 drug-related incident reports using the Bidirectional Encoder Representations from Transformers and its derivatives. Based on the P-mSHELL model, a comprehensive framework for incident factor analysis, we established seven distinct factor categories and evaluated various pre-trained models through five-fold cross-validation. Almost all models achieved macro F1 scores exceeding 0.6, with the lightweight A Lite BERT model showing comparable performance to BERT. This study demonstrates the practical feasibility of natural language processing techniques for systematic incident factor analysis, supporting enhanced patient safety management.

Authors

  • Yuri Takamatsu
    Division of Drug Informatics, Keio University Faculty of Pharmacy.
  • Sayaka Ebara
    Division of Drug Informatics, Keio University Faculty of Pharmacy.
  • Hayato Kizaki
    Keio University Faculty of Pharmacy, Division of Drug Informatics, Tokyo, Japan.
  • Satoshi Watabe
    Division of Drug Informatics, Keio University Faculty of Pharmacy, Tokyo, Japan.
  • Shungo Imai
    Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
  • Shuntaro Yada
    Graduate School of Science and Technology, Nara Institute of Science and Technology, Ikoma, Nara, Japan.
  • Eiji Aramaki
    Nara Institute of Science and Technology (NAIST), Japan.
  • Osamu Yasumuro
    Department of Pharmacy, Kameda General Hospital.
  • Ryohkan Funakoshi
    Department of Pharmacy, Kameda General Hospital.
  • Satoko Hori
    Keio University Faculty of Pharmacy, Division of Drug Informatics, Tokyo, Japan.