Optimizing artificial neural network models for metabolomics and systems biology: an example using HPLC retention index data.

Journal: Bioanalysis
Published Date:

Abstract

BACKGROUND: Artificial Neural Networks (ANN) are extensively used to model 'omics' data. Different modeling methodologies and combinations of adjustable parameters influence model performance and complicate model optimization.

Authors

  • L Mark Hall
    Hall Associates Consulting, Quincy, MA, USA.
  • Dennis W Hill
  • Lochana C Menikarachchi
  • Ming-Hui Chen
  • Lowell H Hall
  • David F Grant