Machine-learning-based artificial intelligence tools for the diagnosis of tropical fevers: a systematic review and meta-analysis protocol of diagnostic test accuracy.

Journal: BMJ open
Published Date: Aug 25, 2025

Abstract

INTRODUCTION: Recent advancements in diagnosing tropical fevers increasingly use artificial intelligence (AI). These innovations focus on diagnosing single or multiple diseases, significantly reducing the global burden of tropical fevers. This protocol helps to identify the key factors required for a systematic review of AI-based machine learning (ML) diagnostic test accuracy-based studies to obtain a view on the pooled performance of different types of available tools. This systematic review protocol aims to review the type of ML-based AI tools and pool the performance metrics of the currently available ML-based AI devices.

Authors

  • Shravya Chitrapady
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Rajalakshmi Rajendran
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Haritha K
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Tejashree M U
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Muhammed Rashid
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India.
  • Pooja Gopal Poojari
    Department of Pharmacy Practice, Srinivas College of Pharmacy, Mangaluru, Karnataka, India.
  • Vijayanarayana K
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Muralidhar Varma
    Department of Infectious Disease, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Vasudha Devi
    Department of Pharmacology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Dinesh Acharya
    Department of Computer Science and Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, India.
  • Sohil Khan
    Pharmacotherapeutics and Evidence Based Practice, Griffith University School of Pharmacy and Medical Sciences, Gold Coast, Queensland, Australia.
  • Girish Thunga
    Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. Electronic address: girish.thunga@manipal.edu.

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