BiobankConnect: software to rapidly connect data elements for pooled analysis across biobanks using ontological and lexical indexing.

Journal: Journal of the American Medical Informatics Association : JAMIA
PMID:

Abstract

OBJECTIVE: Pooling data across biobanks is necessary to increase statistical power, reveal more subtle associations, and synergize the value of data sources. However, searching for desired data elements among the thousands of available elements and harmonizing differences in terminology, data collection, and structure, is arduous and time consuming.

Authors

  • Chao Pang
    University of Groningen, University Medical Centre Groningen, Genomics Coordination Centre, Department of Genetics, Groningen, The Netherlands, University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands and.
  • Dennis Hendriksen
    University of Groningen, University Medical Centre Groningen, Genomics Coordination Centre, Department of Genetics, Groningen, The Netherlands.
  • Martijn Dijkstra
    Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • K Joeri van der Velde
    Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Groningen Bioinformatics Center, University of Groningen, Groningen, The Netherlands.
  • Joel Kuiper
    Department of Genetics, Genomics Coordination Center, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Hans L Hillege
    Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Morris A Swertz
    University of Groningen, University Medical Centre Groningen, Genomics Coordination Centre, Department of Genetics, Groningen, The Netherlands, University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands and LifeLines Cohort Study and Biobank, Groningen, The Netherlands m.a.swertz@rug.nl.