Representing virus-host interactions and other multi-organism processes in the Gene Ontology.

Journal: BMC microbiology
Published Date:

Abstract

BACKGROUND: The Gene Ontology project is a collaborative effort to provide descriptions of gene products in a consistent and computable language, and in a species-independent manner. The Gene Ontology is designed to be applicable to all organisms but up to now has been largely under-utilized for prokaryotes and viruses, in part because of a lack of appropriate ontology terms.

Authors

  • R E Foulger
    European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. rebecca.foulger@ucl.ac.uk.
  • D Osumi-Sutherland
    European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. davidos@ebi.ac.uk.
  • B K McIntosh
    Department of Biochemistry and Biophysics, Texas Agrilife Research, Texas A&M University, College Station, TX, 77843, USA. brenley@mit.edu.
  • C Hulo
    Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel-Servet, 1211, Geneva 4, Switzerland. Chantal.Hulo@isb-sib.ch.
  • P Masson
    Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel-Servet, 1211, Geneva 4, Switzerland. patrick.masson@isb-sib.ch.
  • S Poux
    Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel-Servet, 1211, Geneva 4, Switzerland. sylvain.poux@isb-sib.ch.
  • P Le Mercier
    Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 Rue Michel-Servet, 1211, Geneva 4, Switzerland. Philippe.Lemercier@isb-sib.ch.
  • J Lomax
    European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. jane@ebi.ac.uk.