AIMC Topic: Viruses

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Charting the virosphere: computational synergies of AI and bioinformatics in viral discovery and evolution.

Journal of virology
The advancement of metagenomic sequencing has revealed a vast viral diversity while simultaneously exposing limitations of homology-based tools such as BLAST and HMMER, which often fail to detect highly divergent viral genomes. The integration of art...

Curvature-Sensing Peptides for Virus and Extracellular Vesicle Applications.

ACS nano
Membrane curvature is a key biophysical feature that regulates diverse biological processes. A wide range of natural proteins have distinct structural motifs that can sense membrane curvature and function independently as curvature-sensing peptides. ...

Viral interferon antagonism shapes host tropism.

PLoS pathogens
Outbreaks of zoonotic viruses in human populations highlight the need to understand the molecular factors that influence viral host tropism and interspecies transmission. A virus's host range is determined not only by the expression of host factors t...

Global wastewater microbiome reveals core bacterial community and viral diversity with regional antibiotic resistance patterns.

mSystems
Municipal wastewater treatment plants (WWTPs) serve as global repositories for diverse and dynamic microbial communities, reflecting the complex interplay of human activities, environmental conditions, and public health challenges. Despite their impo...

Viral community succession during cadaver decomposition and its potential for estimating postmortem intervals.

Applied and environmental microbiology
UNLABELLED: Microbial communities play a vital role in cadaver decomposition and serve as reliable tools for postmortem interval (PMI) estimation. However, current research focuses primarily on bacterial/fungal communities, though viruses-as Earth's ...

Recent advances in organic molecule fluorescent probes for microbial imaging.

Journal of materials chemistry. B
Microorganisms play a crucial role in human life and production. However, certain pathogenic microorganisms, such as bacteria, viruses, and fungi, can cause diseases like pneumonia, meningitis, and influenza, potentially leading to global public heal...

Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection.

Biosensors & bioelectronics
The integration of synthetic biology with biosensor technologies has catalyzed a paradigm shift in the development of programmable, field-deployable diagnostic systems for precision detection of pathogens and viral threats. This review provides a com...

SERS technology in virus Detection: Advances, challenges, and future perspectives.

Biosensors & bioelectronics
SERS has revolutionized viral detection with its high sensitivity and specificity. This review comprehensively explores the application progress, challenges, and future directions of SERS in viral detection. Firstly, the fundamental principles of SER...

A Benchmark for Virus Infection Reporter Virtual Staining in Fluorescence and Brightfield Microscopy.

Scientific data
Detecting virus-infected cells in light microscopy requires a reporter signal commonly achieved by immunohistochemistry or genetic engineering. While classification-based machine learning approaches to the detection of virus-infected cells have been ...

Exploring species taxonomic kingdom using information entropy and nucleotide compositional features of coding sequences based on machine learning methods.

Methods (San Diego, Calif.)
The flow of genetic information from DNA to protein is governed by the central dogma of molecular biology. Genetic drift and mutations usually lead to changes in DNA composition, thereby affecting the coding sequences (CDS) that encode functional pro...