Seq-ing improved gene expression estimates from microarrays using machine learning.

Journal: BMC bioinformatics
Published Date: Sep 4, 2015

Abstract

BACKGROUND: Quantifying gene expression by RNA-Seq has several advantages over microarrays, including greater dynamic range and gene expression estimates on an absolute, rather than a relative scale. Nevertheless, microarrays remain in widespread use, demonstrated by the ever-growing numbers of samples deposited in public repositories.

Authors

  • Paul K Korir
    School of Biochemistry and Cell Biology, University College Cork, Western Road, Cork, Ireland. paul.korir@gmail.com.
  • Paul Geeleher
    Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL-60637, USA. paul.geeleher@gmail.com.
  • Cathal Seoighe
    School of Mathematics, Statistics and Applied Mathematics, University Road, Galway, Ireland. cathal.seoighe@nuigalway.ie.

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