Test-retest reliability of fMRI experiments during robot-assisted active and passive stepping.

Journal: Journal of neuroengineering and rehabilitation
Published Date: Nov 17, 2015

Abstract

BACKGROUND: Brain activity has been shown to undergo cortical and sub-cortical functional reorganisation over the course of gait rehabilitation in patients suffering from a spinal cord injury or a stroke. These changes however, have not been completely elucidated by neuroimaging to date, mainly due to the scarcity of long-term, follow-up investigations. The magnetic resonance imaging (MRI) compatible stepper MARCOS was specifically developed to enable the investigation of the supraspinal adaptations in paretic patients undergoing gait-rehabilitation in a controlled and repeatable manner. In view of future clinical research, the present study aims at examining the test-retest reliability of functional MRI (fMRI) experiments using MARCOS.

Authors

  • Lukas Jaeger
    Department of Health Sciences and Technology, Sensory-Motor Systems (SMS) Lab, ETH Zurich, ML G 59, Sonneggstrasse 3, 8092, Zurich, Switzerland. lukas.jaeger@hest.ethz.ch.
  • Laura Marchal-Crespo
    Department of Health Sciences and Technology, Sensory-Motor Systems (SMS) Lab, ETH Zurich, ML G 59, Sonneggstrasse 3, 8092, Zurich, Switzerland. laura.marchal@hest.ethz.ch.
  • Peter Wolf
    Department of Health Sciences and Technology, Sensory-Motor Systems (SMS) Lab, ETH Zurich, ML G 59, Sonneggstrasse 3, 8092, Zurich, Switzerland. peter.wolf@hest.ethz.ch.
  • Robert Riener
    Sensory-Motor Systems Lab, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
  • Spyros Kollias
    Clinic of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland. spyros.kollias@usz.ch.
  • Lars Michels
    Clinic of Neuroradiology, University Hospital of Zurich, Zurich, Switzerland. lars.michels@usz.ch.

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