An ontology for major histocompatibility restriction.

Journal: Journal of biomedical semantics
PMID: 26759709

Abstract

BACKGROUND: MHC molecules are a highly diverse family of proteins that play a key role in cellular immune recognition. Over time, different techniques and terminologies have been developed to identify the specific type(s) of MHC molecule involved in a specific immune recognition context. No consistent nomenclature exists across different vertebrate species.

Authors

  • Randi Vita
    La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
  • James A Overton
    La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.
  • Emily Seymour
    La Jolla Institute for Allergy and Immunology, 9420 Athena Circle La Jolla, San Diego, California 92037 USA.
  • John Sidney
    La Jolla Institute for Allergy and Immunology, 9420 Athena Circle La Jolla, San Diego, California 92037 USA.
  • Jim Kaufman
    University of Cambridge, Trinity Ln, Cambridge, CB2 1TN UK.
  • Rebecca L Tallmadge
    Cornell University College of Veterinary Medicine, Ithaca, New York 14853-6401 USA.
  • Shirley Ellis
    The Pirbright Institute, Ash Rd, Woking, GU24 0NF UK.
  • John Hammond
    The Pirbright Institute, Ash Rd, Woking, GU24 0NF UK.
  • Geoff W Butcher
    The Babraham Institute, Cambridge, CB22 3AT UK.
  • Alessandro Sette
    La Jolla Institute for Allergy and Immunology, 9420 Athena Circle La Jolla, San Diego, California 92037 USA.
  • Bjoern Peters
    La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America.

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