Will they participate? Predicting patients' response to clinical trial invitations in a pediatric emergency department.

Journal: Journal of the American Medical Informatics Association : JAMIA
Published Date: Jul 1, 2016

Abstract

OBJECTIVE: (1) To develop an automated algorithm to predict a patient's response (ie, if the patient agrees or declines) before he/she is approached for a clinical trial invitation; (2) to assess the algorithm performance and the predictors on real-world patient recruitment data for a diverse set of clinical trials in a pediatric emergency department; and (3) to identify directions for future studies in predicting patients' participation response.

Authors

  • Yizhao Ni
    Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
  • Andrew F Beck
    Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
  • Regina Taylor
    Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
  • Jenna Dyas
    Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.
  • Imre Solti
    Department of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA James M Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Jacqueline Grupp-Phelan
    Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.
  • Judith W Dexheimer
    Department of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Division of Pediatric Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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