Neural correlates of motor recovery after robot-assisted stroke rehabilitation: a case series study.

Journal: Neurocase
Published Date: Oct 1, 2016

Abstract

Robot-assisted bilateral arm therapy (RBAT) has shown promising results in stroke rehabilitation; however, connectivity mapping of the sensorimotor networks after RBAT remains unclear. We used fMRI before and after RBAT and a dose-matched control intervention (DMCI) to explore the connectivity changes in 6 subacute stroke patients. Sensorimotor functions improved in the RBAT and DMCI groups after treatment. Enhanced activation changes were observed in bilateral primary motor cortex (M1) and bilateral supplementary motor area (SMA) after RBAT. Dynamic causal model analysis revealed that interhemispheric connections were enhanced in RBAT patients. These preliminary findings suggest that intracortical and intercortical coupling might underlie poststroke RBAT.

Authors

  • Yang-Teng Fan
    a School of Occupational Therapy, College of Medicine , National Taiwan University , Taipei , Taiwan.
  • Keh-chung Lin
    School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
  • Ho-Ling Liu
    c Department of Medical Imaging and Radiological Sciences , Chang Gung University , Taoyuan , Taiwan.
  • Ching-yi Wu
    Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, 259 Wenhua 1st Rd, Taoyuan, Taiwan. cywu@mail.cgu.edu.tw.
  • Yau-Yau Wai
    g Department of Diagnostic Radiology , Chang Gung Memorial Hospital , Keelung , Taiwan.
  • Tsong-Hai Lee
    i Department of Neurology and Stroke Center , Chang Gung Memorial Hospital , Taoyuan , Taiwan.

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