GeneSCF: a real-time based functional enrichment tool with support for multiple organisms.

Journal: BMC bioinformatics
Published Date:

Abstract

BACKGROUND: High-throughput technologies such as ChIP-sequencing, RNA-sequencing, DNA sequencing and quantitative metabolomics generate a huge volume of data. Researchers often rely on functional enrichment tools to interpret the biological significance of the affected genes from these high-throughput studies. However, currently available functional enrichment tools need to be updated frequently to adapt to new entries from the functional database repositories. Hence there is a need for a simplified tool that can perform functional enrichment analysis by using updated information directly from the source databases such as KEGG, Reactome or Gene Ontology etc.

Authors

  • Santhilal Subhash
    Department of Medical Genetics, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-40530, Sweden.
  • Chandrasekhar Kanduri
    Department of Medical Genetics, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, SE-40530, Sweden. kanduri.chandrasekhar@gu.se.