Gene Ontology synonym generation rules lead to increased performance in biomedical concept recognition.

Journal: Journal of biomedical semantics
Published Date:

Abstract

BACKGROUND: Gene Ontology (GO) terms represent the standard for annotation and representation of molecular functions, biological processes and cellular compartments, but a large gap exists between the way concepts are represented in the ontology and how they are expressed in natural language text. The construction of highly specific GO terms is formulaic, consisting of parts and pieces from more simple terms.

Authors

  • Christopher S Funk
    Computational Bioscience, University of Colorado School of Medicine, Aurora, CO 80045, USA. christopher.funk@ucdenver.edu.
  • K Bretonnel Cohen
    Computational Bioscience, University of Colorado School of Medicine, Aurora, CO 80045, USA.
  • Lawrence E Hunter
    Computational Bioscience Program and Department of Pharmacology, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado 80045, USA.
  • Karin M Verspoor
    Department of Computing and Information Systems, University of Melbourne, Parkville, Melbourne, 3010, Australia.