Precuneus functioning differentiates first-episode psychosis patients during the fantasy movie Alice in Wonderland.

Journal: Psychological medicine
Published Date: Feb 1, 2017

Abstract

BACKGROUND: While group-level functional alterations have been identified in many brain regions of psychotic patients, multivariate machine-learning methods provide a tool to test whether some of such alterations could be used to differentiate an individual patient. Earlier machine-learning studies have focused on data collected from chronic patients during rest or simple tasks. We set out to unravel brain activation patterns during naturalistic stimulation in first-episode psychosis (FEP).

Authors

  • E Rikandi
    Mental Health Unit,National Institute for Health and Welfare,Helsinki,Finland.
  • S Pamilo
    Department of Neuroscience and Biomedical Engineering, andAdvanced Magnetic Imaging Centre,Aalto NeuroImaging,Aalto University School of Science,Espoo,Finland.
  • T Mäntylä
    Mental Health Unit,National Institute for Health and Welfare,Helsinki,Finland.
  • J Suvisaari
    Mental Health Unit,National Institute for Health and Welfare,Helsinki,Finland.
  • T Kieseppä
    Mental Health Unit,National Institute for Health and Welfare,Helsinki,Finland.
  • R Hari
    Department of Neuroscience and Biomedical Engineering, andAdvanced Magnetic Imaging Centre,Aalto NeuroImaging,Aalto University School of Science,Espoo,Finland.
  • M Seppä
    Department of Neuroscience and Biomedical Engineering, andAdvanced Magnetic Imaging Centre,Aalto NeuroImaging,Aalto University School of Science,Espoo,Finland.
  • T T Raij
    Department of Neuroscience and Biomedical Engineering, andAdvanced Magnetic Imaging Centre,Aalto NeuroImaging,Aalto University School of Science,Espoo,Finland.

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