Swallowing a Surgeon: Toward Clinical Nanorobots.

Journal: Accounts of chemical research
PMID: 28945409

Abstract

In this Account, "a step toward clinical nanorobots" is proposed as one of the Holy Grails in chemistry, which could lead to a great leap in the field of biomedicines when accomplished. We review our preliminary contributions to this challenge by engineering chaperonin protein GroEL to generate de novo structures and functions.

Authors

  • Seunghyun Sim
    Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
  • Takuzo Aida
    Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

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