Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
PMID: 38525642

Abstract

BACKGROUND: Progressive interventions have recently improved programmatic outcomes in drug-resistant tuberculosis (DR-TB) care in South Africa (SA). Amidst these, a shorter regimen was introduced in 2017 with weak evidence, and has shown mixed results. Outcomes still fall short of national targets, and the coronavirus disease 2019 pandemic has undermined progress to date.

Authors

  • J-D K Lotz
    Department of Family Medicine and Rural Health, Walter Sisulu University, Mthatha, South Africa, Madwaleni District Hospital, Elliotdale, South Africa. jdlotz@gmail.com.
  • J Porter
    Department of Family Medicine and Rural Health, Walter Sisulu University, Mthatha, South Africa, Division of Family Medicine, Department of Family, Community, and Emergency Care, University of Cape Town, South Africa, False Bay District Hospital, Cape Town, South Africa. dr.james.porter@gmail.com.
  • H Conradie
    Department of Family Medicine and Primary Care, Stellenbosch University, Cape Town, South Africa. hoffie@sun.ac.za.
  • T Boyles
    Right to Care, Centurion, South Africa, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa, London School of Hygiene and Tropical Medicine, London, United Kingdom. drtomboyles@gmail.com.
  • B Gaunt
    Zithulele District Hospital, Coffee Bay, South Africa. gaunts@gmail.com.
  • S Dimanda
    Madwaleni District Hospital, Elliotdale, South Africa. sinovuyodimanda1994@gmail.com.
  • D Cort
    Department of Sociology, University of Massachusetts, Amherst, USA. dcort@soc.umass.edu.

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