Framework for detection and localization of coronary non-calcified plaques in cardiac CTA using mean radial profiles.

Journal: Computers in biology and medicine
Published Date:

Abstract

BACKGROUND AND OBJECTIVE: The high mortality rate associated with coronary heart disease (CHD) has driven intensive research in cardiac imaging and image analysis. The advent of computed tomography angiography (CTA) has turned non-invasive diagnosis of cardiovascular anomalies into reality as calcified coronary plaques can be easily identified due to their high intensity values. However, the detection of non-calcified plaques in CTA is still a challenging problem because of lower intensity values, which are often similar to the nearby blood and muscle tissues. In this work, we propose the use of mean radial profiles for the detection of non-calcified plaques in CTA imagery.

Authors

  • Muhammad Moazzam Jawaid
    City University of London, Northampton Square, London EC1V 0HB, UK; Mehran University of Engineering & Technology, Jamshoro, Pakistan. Electronic address: muhammad.jawaid.2@city.ac.uk.
  • Atif Riaz
    City University of London, Northampton Square, London EC1V 0HB, UK.
  • Ronak Rajani
    St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.
  • Constantino Carlos Reyes-Aldasoro
    Senior Lecturer in Biomedical Image Analysis giCentre, Department of Computer Science, School of Science and Technology City, University of London, London, United Kingdom.
  • Greg Slabaugh
    Digital Environment Research Institute, Queen Mary University of London, London, United Kingdom.