Identification of differentially expressed genes regulated by molecular signature in breast cancer-associated fibroblasts by bioinformatics analysis.

Journal: Archives of gynecology and obstetrics
Published Date:

Abstract

OBJECTIVE: Breast cancer is a severe risk to public health and has adequately convoluted pathogenesis. Therefore, the description of key molecular markers and pathways is of much importance for clarifying the molecular mechanism of breast cancer-associated fibroblasts initiation and progression. Breast cancer-associated fibroblasts gene expression dataset was downloaded from Gene Expression Omnibus database.

Authors

  • Basavaraj Vastrad
    Department of Pharmaceutics, SET's College of Pharmacy, Dharwad, Karnataka, 580002, India. basavarajmv@gmail.com.
  • Chanabasayya Vastrad
    Department of Computer Science, Karnataka University, Dharwad, Karnataka, 580002, India.
  • Anandkumar Tengli
    Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University Mysuru, Mysuru, Karnataka, 570015, India.
  • Sudhir Iliger
    Department of Pharmaceutics, SET's College of Pharmacy, Dharwad, Karnataka, 580002, India.