Towards refactoring the Molecular Function Ontology with a UML profile for function modeling.

Journal: Journal of biomedical semantics
Published Date:

Abstract

BACKGROUND: Gene Ontology (GO) is the largest resource for cataloging gene products. This resource grows steadily and, naturally, this growth raises issues regarding the structure of the ontology. Moreover, modeling and refactoring large ontologies such as GO is generally far from being simple, as a whole as well as when focusing on certain aspects or fragments. It seems that human-friendly graphical modeling languages such as the Unified Modeling Language (UML) could be helpful in connection with these tasks.

Authors

  • Patryk Burek
    Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, Leipzig, 04107, Germany.
  • Frank Loebe
    Computer Science Institute, University of Leipzig, Augustusplatz 10, Leipzig, 04109, Germany. frank.loebe@informatik.uni-leipzig.de.
  • Heinrich Herre
    Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.