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Towards refactoring the Molecular Function Ontology with a UML profile for function modeling.

Journal of biomedical semantics
BACKGROUND: Gene Ontology (GO) is the largest resource for cataloging gene products. This resource grows steadily and, naturally, this growth raises issues regarding the structure of the ontology. Moreover, modeling and refactoring large ontologies s...

Evidence of Rentian Scaling of Functional Modules in Diverse Biological Networks.

Neural computation
Biological networks have long been known to be modular, containing sets of nodes that are highly connected internally. Less emphasis, however, has been placed on understanding how intermodule connections are distributed within a network. Here, we bor...

Flexible model of network embedding.

Scientific reports
There has lately been increased interest in describing complex systems not merely as single networks but rather as collections of networks that are coupled to one another. We introduce an analytically tractable model that enables one to connect two l...

The Construction and Development of App Application Platform for Public Information Products of Urban Grand Media in the Context of Artificial Intelligence.

Computational and mathematical methods in medicine
This paper conducts in-depth research and analysis on the construction of the public information product APP application platform of urban big media in the context of artificial intelligence and discusses its development. Based on the improvement of ...

KG2Vec: A node2vec-based vectorization model for knowledge graph.

PloS one
Since the word2vec model was proposed, many researchers have vectorized the data in the research field based on it. In the field of social network, the Node2Vec model improved on the basis of word2vec can vectorize nodes and edges in social networks,...

HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks.

Briefings in bioinformatics
Identifying new indications for drugs plays an essential role at many phases of drug research and development. Computational methods are regarded as an effective way to associate drugs with new indications. However, most of them complete their tasks ...

Breast cancer patient characterisation and visualisation using deep learning and fisher information networks.

Scientific reports
Breast cancer is the most commonly diagnosed female malignancy globally, with better survival rates if diagnosed early. Mammography is the gold standard in screening programmes for breast cancer, but despite technological advances, high error rates a...

MHADTI: predicting drug-target interactions via multiview heterogeneous information network embedding with hierarchical attention mechanisms.

Briefings in bioinformatics
MOTIVATION: Discovering the drug-target interactions (DTIs) is a crucial step in drug development such as the identification of drug side effects and drug repositioning. Since identifying DTIs by web-biological experiments is time-consuming and costl...

A geometric deep learning framework for drug repositioning over heterogeneous information networks.

Briefings in bioinformatics
Drug repositioning (DR) is a promising strategy to discover new indicators of approved drugs with artificial intelligence techniques, thus improving traditional drug discovery and development. However, most of DR computational methods fall short of t...

Technological trends in Swedish medical libraries.

Health information and libraries journal
Medical libraries in Sweden are digitised to a large extent, technically advanced and developing rapidly. This paper investigates technological trends among Swedish medical libraries in the near and distant future and their application within differe...