The bacterial interlocked process ONtology (BiPON): a systemic multi-scale unified representation of biological processes in prokaryotes.

Journal: Journal of biomedical semantics
Published Date: Nov 23, 2017

Abstract

BACKGROUND: High-throughput technologies produce huge amounts of heterogeneous biological data at all cellular levels. Structuring these data together with biological knowledge is a critical issue in biology and requires integrative tools and methods such as bio-ontologies to extract and share valuable information. In parallel, the development of recent whole-cell models using a systemic cell description opened alternatives for data integration. Integrating a systemic cell description within a bio-ontology would help to progress in whole-cell data integration and modeling synergistically.

Authors

  • Vincent J Henry
    Laboratoire de Recherche en Informatique (LRI), UMR 8623, CNRS, Université Paris-Sud/Université Paris-Saclay, Orsay, France.
  • Anne Goelzer
    INRA, UR1404, MaIAGE, Université Paris-Saclay, Jouy-en-Josas, France. Anne.Goelzer@inra.fr.
  • Arnaud Ferré
    Laboratoire de Recherche en Informatique (LRI), UMR 8623, CNRS, Université Paris-Sud/Université Paris-Saclay, Orsay, France.
  • Stephan Fischer
    INRA, UR1404, MaIAGE, Université Paris-Saclay, Jouy-en-Josas, France.
  • Marc Dinh
    INRA, UR1404, MaIAGE, Université Paris-Saclay, Jouy-en-Josas, France.
  • Valentin Loux
    INRA, UR1404, MaIAGE, Université Paris-Saclay, Jouy-en-Josas, France.
  • Christine Froidevaux
    Laboratoire de Recherche en Informatique (LRI), UMR 8623, CNRS, Université Paris-Sud/Université Paris-Saclay, Orsay, France.
  • Vincent Fromion
    INRA, UR1404, MaIAGE, Université Paris-Saclay, Jouy-en-Josas, France.

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