CNN-BLPred: a Convolutional neural network based predictor for β-Lactamases (BL) and their classes.
Journal:
BMC bioinformatics
Published Date:
Dec 28, 2017
Abstract
BACKGROUND: The β-Lactamase (BL) enzyme family is an important class of enzymes that plays a key role in bacterial resistance to antibiotics. As the newly identified number of BL enzymes is increasing daily, it is imperative to develop a computational tool to classify the newly identified BL enzymes into one of its classes. There are two types of classification of BL enzymes: Molecular Classification and Functional Classification. Existing computational methods only address Molecular Classification and the performance of these existing methods is unsatisfactory.