Untargeted metabolomic profiling in children identifies novel pathways in asthma and atopy.

Journal: The Journal of allergy and clinical immunology
PMID: 38344970

Abstract

BACKGROUND: Asthma and other atopic disorders can present with varying clinical phenotypes marked by differential metabolomic manifestations and enriched biological pathways.

Authors

  • Stéphanie Lejeune
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif; University of Lille, Pediatric Pulmonology and Allergy Department, Hôpital Jeanne de Flandre, CHU Lille, Lille, France; University of Lille, INSERM Unit 1019, CNRS UMR 9017, CHU Lille, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France. Electronic address: stephanie.lejeune@chu-lille.fr.
  • Abhinav Kaushik
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif; Department of Environmental Health, T. H. Chan School of Public Health, Harvard University, Boston, Mass.
  • Ella S Parsons
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif.
  • Sharon Chinthrajah
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif.
  • Michael Snyder
    Department of Genetics, Stanford University School of Medicine, Stanford, Calif.
  • Manisha Desai
    Quantitative Science Unit, Department of Medicine, Stanford University School of Medicine, Stanford, Calif.
  • Monali Manohar
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif.
  • Mary Prunicki
    Department of Medicine, Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif; Department of Environmental Health, T. H. Chan School of Public Health, Harvard University, Boston, Mass.
  • Kévin Contrepois
    Department of Genetics, Stanford University School of Medicine, Stanford, Calif.
  • Philippe Gosset
    University of Lille, INSERM Unit 1019, CNRS UMR 9017, CHU Lille, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.
  • Antoine Deschildre
    University of Lille, Pediatric Pulmonology and Allergy Department, Hôpital Jeanne de Flandre, CHU Lille, Lille, France; University of Lille, INSERM Unit 1019, CNRS UMR 9017, CHU Lille, Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.
  • Kari Nadeau
    Department of Environmental Health, T. H. Chan School of Public Health, Harvard University, Boston, Mass.

Keywords

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