Neonatal Seizure Detection Using Deep Convolutional Neural Networks.

Journal: International journal of neural systems
Published Date:

Abstract

Identifying a core set of features is one of the most important steps in the development of an automated seizure detector. In most of the published studies describing features and seizure classifiers, the features were hand-engineered, which may not be optimal. The main goal of the present paper is using deep convolutional neural networks (CNNs) and random forest to automatically optimize feature selection and classification. The input of the proposed classifier is raw multi-channel EEG and the output is the class label: seizure/nonseizure. By training this network, the required features are optimized, while fitting a nonlinear classifier on the features. After training the network with EEG recordings of 26 neonates, five end layers performing the classification were replaced with a random forest classifier in order to improve the performance. This resulted in a false alarm rate of 0.9 per hour and seizure detection rate of 77% using a test set of EEG recordings of 22 neonates that also included dubious seizures. The newly proposed CNN classifier outperformed three data-driven feature-based approaches and performed similar to a previously developed heuristic method.

Authors

  • Amir H Ansari
    1 Department of Electrical Engineering, KU Leuven, 3001 Leuven, Belgium.
  • Perumpillichira J Cherian
    3 Department of Neurology, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.
  • Alexander Caicedo
    Katholieke Universiteit Leuven.
  • Gunnar Naulaers
    5 Neonatal Intensive Care Unit, University Hospitals Leuven, Belgium.
  • Maarten De Vos
    STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics-Department of Electrical Engineering (ESAT), KU Leuven, Leuven, Belgium. maarten.devos@kuleuven.be.
  • Sabine Van Huffel
    Katholieke Universiteit Leuven.